Pre-Menopausal PANEL (for menstruating women)

Research has demonstrated that free hormone fraction predominates in saliva. Hormones can be found here in a free (biologically active) form that influences living cells. The salivary female hormone levels correlate with the free hormone levels in the tissues. The female hormonal panel gives a good estimate of the ovarian function over a whole menstrual cycle.

The two major classes of ovarian hormones released during the menstrual cycle are progesterone and estrogens, which are named female steroid hormones. The most active estrogen is estradiol, while the most active progestin is progesterone. The female cycle has three physiologic phases:

follicular (starts with the onset of menstrual blood flow, is of variable time, and is characterized by both low progesterone and estrogen output),

  • ovulation (one-three days long, in which the egg is released, and this period is characterized by high levels of estrogen)
  • luteal (usually lasting 12-14 days and ending with menses, characterized by high level of progesterone and moderate increase in levels of estrogen)

Estrogens and progesterone affect several target organs involved in successful conception and pregnancy, as well as a number of secondary sexual characteristics such as soft skin, reduced body hair and its distribution, a higher voice pitch, release of pheromones, etc. The principal target organs of estrogens and progesterone are: uterus, fallopian tubes, vagina, external genitalia, breasts, liver, kidneys, skin and bones.

The female hormonal test is a simple, non-invasive test. Eleven saliva samples are collected during specified time period throughout the menstrual cycle. The diagnostic guesswork is minimized, allowing for hormonal balance evaluation and according to results individual, customized treatment for each female patient. For instance detection of luteal phase hormonal imbalance usually is associated with PMS, fibroids, menstrual problems that may originate in the brain, menstrual cycle irregularities following the use of birth control pills, migraine headaches, endometriosis, polycystic ovary disease, early osteoporosis, and other female hormonal problems, even infertility or spontaneous miscarriage.

Currently, female hormone therapy is not individualized to the needs of each woman and most women are empirically treated without regard to their physiology and specific needs. Female hormonal panel allows a clinician to appropriately customize therapy to balance female sex hormones.


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Marek Gawrysz, MD

Marek Gawrysz, MD

I earned my medical degree from the Medical Academy in Krakow (Collegium Medicum of the Jagiellonian University), Poland in 1978. My training requirements were fulfilled at the Medical Academy in Krakow, Poland, Swedish Covenant Hospital and Columbus-Cuneo-Cabrini Medical Center in Chicago. I am board certified and have dual fellowship (extra training) in Family Practice and Anti-aging, Regenerative and Functional Medicine.

I am practicing medicine for 35 years.

I am also a recipient of 2012, 2011 and 2010 People's Choice, Most Compassionate Doctor 2011, and 2003 Physician of the Year awards.

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American Academy of Anti-Aging MedicineFellowship in Anti-Aging, Regenerative & Functional MedicineAmerican Academy of Family PhysiciansAmerican Board of Physician SpecialtiesJagiellonian UniversityPolish-American Medical Society
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